Interaction of Caffeine With Regadenoson-Induced Hyperemic Myocardial Blood Flow as Measured by Positron Emission Tomography

Interaction of caffeine with regadenoson-induced hyperemic myocardial blood flow as measured by positron emission tomography: a randomized, double-blind, placebo-controlled crossover trial.

Positron Emission Tomography-Determined Hyperemic Flow, Myocardial Flow Reserve, and Flow Gradient—Quo Vadis?

Positron emission tomography/computed tomography (PET/CT) applied with positron-emitting flow tracers such as 13N-ammonia and 82Rubidium enables the quantification of both myocardial perfusion and myocardial blood flow (MBF) in milliliters per gram per minute for coronary artery disease (CAD) detection and characterization. The detection of a regional myocardial perfusion defect during vasomoto...

Changes in human cerebral blood flow and myocardial blood flow during mental stress measured by dual positron emission tomography.

Mental stress causes a substantial sympathetic response, thus increasing myocardial blood flow (MBF). However, the effects of mental stress on global CBF have not been elucidated. In this study, changes in CBF and MBF in relation to mental stress were measured by a dual positron emission tomography system that can measure CBF and MBF simultaneously. CBF and MBF were measured in 10 healthy men w...

In vivo quantitation of regional myocardial blood flow by positron-emission computed tomography.

was determined by the arterial reference technique in vivo and in vitro. Together with gamma-emitting Ce-141 microspheres, positron-emitting Ga-68-labeled microspheres were injected into the left atrium and their myocardial concentrations determined in vivo from gated and ungated cross-sectional PCT images. The loss in count recovery related to object size was corrected using postmortem and in ...

Assessment of Regional Myocardial and Renal Blood Flow With CoppermPTSM and Positron Emission Tomography

We recently demonstrated in isolated, perfused hearts that radiolabeled pyruvaldehyde bis(N4-methylthiosemicarbazonato)copper(II) (Cu-PTSM) is well extracted throughout a range of conditions including ischemia, hypoxia, and hyperemia. Once extracted, binding of radioactivity by the isolated heart was essentially irreversible, giving this tracer microspherelike qualities. Because Cu-PTSM can be ...